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Anti-GADD153 Polyclonal Antibody

產(chǎn)品簡(jiǎn)介：

Anti-GADD153 Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:25-100.
交叉反應(yīng)Human

產(chǎn)品型號(hào)：K106765P

更新時(shí)間：2022-08-14

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

Anti-GADD153 Polyclonal Antibody

英文名稱	Anti-GADD153 Polyclonal Antibody
宿主	Rabbit
別名	CEBPZ;CHOP;CHOP-10;CHOP10;GADD153;C/EBPzeta;DNA damage inducible transcript 3
應(yīng)用	IHC
稀釋比例	IHC 1:25-100.
交叉反應(yīng)	Human
蛋白分子量	19kDa
Gene ID	1649
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human GADD153
性狀	液體
Public Immunogen Range	A synthetic peptide of human GADD153
Subcellular Locations	Nucleus Cytoplasm
Swiss Prot	P35638
克隆類型	Polyclonal Antibody
背景資料	This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.